Publications

Publications 2021-2017

E. Gillio Tos, L. Brunasso Cattarello, V. Bortolot, A. Conto

La valutazione del rischio dei prodotti farmaceutici nell’ambiente: un approccio migliorativo

19th Congresso Nazionale della Società Italiana di Tossicologia (SITOX), Bologna
January 2020
A. Conto, E. Gillio Tos, L. Brunasso Cattarello, V. Bortolot

Glicocorticoidi: approcci differenti nel calcolo del valore di PDE e OEL ma risultati simili

19th Congresso Nazionale della Società Italiana di Tossicologia (SITOX), Bologna
January 2020
L. Brunasso Cattarello, V. Bortolot, M. D. Rodda, E. Gillio Tos, A. Conto

Tatuaggi: a che punto siamo?

19th Congresso Nazionale della Società Italiana di Tossicologia (SITOX), Bologna
January 2020
L. Brunasso Cattarello, V. Bortolot, M. D. Rodda, E. Gillio Tos, A. Conto

Nitrosammine: proposta di ranking method per valutare la priorità di valutazione

19th Congresso Nazionale della Società Italiana di Tossicologia (SITOX), Bologna
January 2020
A. Conto

From “in vivo” studies to alternative methods. An update

Chemistry Today, Vol.37(4), pages 14-15
July/August 2019
M. Rodda, E. Gillio Tos, L. Brunasso Cattarello, V. Bortolot, A. Conto

Glucorticoids: different approaches in PDE and OEL evaluation, but similar values.

Toxicology Letters - Special Issue: Abstracts of the 55th Congress of the European Societies of Toxicology
September-October 2019 (Poster)
M. Rodda, E. Gillio Tos, L. Brunasso Cattarello, V. Bortolot, A. Conto

Pharma pollution as a selective pressure

Toxicology Letters - Special Issue: Abstracts of the 55th Congress of the European Societies of Toxicology
September-October 2019 (Poster)
A. Conto

Regulatory Toxicology, indispensable in many regulation: an overview!

Chemistry Today, Vol.37(3), May/June 2019, pages 78-79
June 2019
A. Conto, M.Rodda

L’Environmental Risk Assessment (ERA) dei medicinali ad uso umano. Cos’è, come e quando realizzare questo adempimento previsto dalla linea guida EMA

Linea Guida AFI, Volume VX, Pages 2-59
June 2019
A. Conto

PHARMA INTERMEDIATES. Overbiew on Light Registration Procedure after last deadline.

Chemistry Today, Vol 37(2) pages 32-33
March/April 2019
E. Gillio Tos, M. Rodda, A. Iavello, L. Brunasso Cattarello, I. Barbiero, A. Conto

Determination of health-based exposure limits for a residual active substance based on the method for establishing the Permitted Daily Exposure (PDE). Three years Chemsafe PDE evaluations’ analysis. (POSTER)

58th Annual meeting of the Society of Toxicology, Baltimore (MD – USA)
March 10-14 2019 Poster
M. Rodda, L. Brunasso Cattarello, E. Gillio Tos, A. Conto

The Risk Assessment of pharmaceuticals in the environment: an improved approach. (POSTER)

58th Annual meeting of the Society of Toxicology, Baltimore (MD – USA)
March 10-14 2019 Poster
M. Rodda, L. Brunasso Cattarello, E. Gillio Tos, A. Conto

The Risk Assessment of pharmaceuticals in the environment: an improved approach. The Toxicologist, supplement to Toxicological Sciences – the official journal of the Society of Toxicology (SOT)

Oxford University Press–ISSN 1096-6080, Volume 168
March 2019
E. Gillio Tos, M. Rodda, A. Iavello, L. Brunasso Cattarello, I. Barbiero, A. Conto

Determination of health-based exposure limits for a residual active substance based on the method for establishing the Permitted Daily Exposure (PDE). Three years Chemsafe PDE evaluations’ analysis.

Oxford University Press–ISSN 1096-6080, Volume 168
March 2019
A.Conto

BREXIT and REACH: an overview for a worst case scenario (no deal)

Chemistry Today, Vol. 37(1), page 70-71
January/February 2019
A.Conto

Endocrine Disrupting Chemicals (EDC):a short update

Chemistry today, Vol, 36(5), page 60-62
September/October 2018
A.Conto

BPR impact on SMEs. How to approach a so complex EU Regulation by SMEs.

Chemistry Today, Vol. 36 pages 59/60
May/June 2018
E. Gillio Tos, M. Rodda, A. Iavello, L. Brunasso Cattarello, A. Conto

A homeopathic ophthalmic ointment containing Echinacea purpurea, Euphrasia officinalis and Calendula officinalis extracts: a PDE case report.

54th Congress of the European Societies of Toxicology, Bruxelles (Belgium), Poster
September 2018
A.Conto

Endocrine Disrupting Chemicals: A scientific and regulatory open matter

StoffR (Lexxion) Vol. 3, 2018, pages.116-123
August 2018
A.Conto

Biocidal Regulation Update

Chemistry Today, Vol. 36 pages 53-54
May/June 2018
A.Conto, I. Caldera, M. Rodda

Al. Guideline USP 800, Hazardous drugs handling in healthcare settings.

Buone Pratiche di Fabbricazione, AFI, Volume XIV, Tecniche nuove editore, pag. 343 e successive.
June 2018
A.Conto

REACH, Update for Authorisation and Restriction

Chemistry Today, Vol. 36 pages 31-32
March/April 2018
A.Conto, E. Meriano, Ivo Caldera

Tappa finale per il regolamento REACH.

Notiziario Chimico Farmaceutico, pages 66-71.
March 2018
Conto A, Brunasso Cattarello L, Iavello A, Rodda M, Gillio Tos E.

Acebrophylline: a PDE case report. (With its poster).

The Toxicologist, supplement to Toxicological Sciences - the official journal of the Society Of Toxicology (SOT)
March 2018
Conto A, Brunasso Cattarello L, Iavello A, Rodda M, Gillio Tos E.

Prostaglanid Analogs: PDE assessment and relationship with the therapeutic dose. (With its poster).

The Toxicologist, supplement to Toxicological Sciences - the official journal of the Society Of Toxicology (SOT)
March 2018
Conto A.

Biocidal Products Regulation (BPR)

Unclassifiable Biocides Uses Vol. 35 (6), November/December 2017, pages 26-27
January 2018
Conto A.

Valutare il rischio di farmaci e chemicals. ERA, OEL, OEB, PDE.

ICP n.11, Rivista dell'industria Chimica, pages 14-18
January 2018
Rodda M.; Gillio Tos E.; Iavello A., PhD; Brunasso Cattarello L.; Beccaris F.; Conto A.

Can Occupational Exposure Limits (OEL) be extrapolated from Permitted Daily Exposure (PDE) and viceversa?

53rd Congress of the European Societies of Toxicology, Bratislava (Slovakia)
September 10-13, 2017
A. Conto et al.

Parametri per la gestione della sicurezza e della qualità di sostanze attive.

Linea Guida AFI, Buone Pratiche di Fabbricazione, Volume XIII, pag. 73
2017

Publications 2016-2012

A. Conto

La valutazione del rischio. Il futuro dell’attività regolatoria. Risk Assessment. The future of the regulatory affairs activity.

NCF Notiziario Chimico Farmaceutico, page 76-78
December 2016
A. Conto et al.

How to assess the PDE values on the basis of toxicological information/data.

PharmaChem, numero 9/10 2016, pages 7-10
September/October 2016
A. Conto

Biocidi: Cosa cambia con il nuovo Regolamento europeo

Notiziario Chimico Farmaceutico, Vol. maggio 2016, pag-50-53
May 2016
A. Conto

Interview. Impurezze genotossiche. Genotossicità? No Grazie! by Giuliana Miglerini

NCF Notiziario Chimico Farmaceutico, page 90-94
February 2016
A. Conto et al.

Le condizioni strettamente controllate (SCC) nella produzione chimico-farmaceutica: non solo requisito per la semplificazione degli adempimenti REACH, ma catalizzatore di sinergie in un sistema integrato di gestione di qualità, sicurezza ed ambiente (2015-2016). Sezione 4, Analisi della normativa e delle linee guide in materia esistenti.

Linea Guida AFI, Buone Pratiche di Fabbricazione, Volume XII, pag. 140
2016
M. Rodda, L. Brunasso, L. Barbiero, A. Conto

Come calcolare i valori di PDE sulla base delle informazioni tossicologiche. a PDE e le relative interazioni  HSE e QA nel settore chimico-farmaceutico.

Linea Guida AFI, Buone Pratiche di fabbricazione, Volume  XI, pag. 160
June 2015
A. Conto et al.

Interview to A. Conto et al. on REACH, CLP and Biocides Regulation

ICP magazine, page  6
June 2014
I. Barbiero, A. Conto

Toxicology & Testing strategies for regulatory purposes

Specialty Chemicals Magazine, page 20-21
March 2014
I. Caldera, A. Conto et al.

Gli allergeni: rischi della salute per il lavoratori e per la qualità dei prodotti.

AFI monography, Volume X, Ed. Techniche nuove, 2014
2014
A. Conto, I. Caldera, G. Coppi et al.

La valutazione dei rischi nel settore farmaceutico in ottica di genere, di età e di provenienza geografica

AFI monography, Volume X, Ed. Techniche nuove, 2014
2014
A. Conto, F. Fasano, A. Basilio, G. Coppi et al.

Considerazioni pratiche sul regolamento biocidi 528/2012/EU

AFI monography, Volume X, Ed. Techniche nuove
2014
A. Conto

Handling Hazaurdous Chemicals and Pharmaceuticals

Reviewed Encyclopedia of Pharmaceutical Technology, IV Edition, Volume 1
Edited by Marcel Dekker Inc., 2011, published in August 2013
A. Conto

The testing approach for the Environmental Risk Assessment (ERA) of Pharmaceuticals

Chemistry Today, vol 30, n. 3 May June 2012, page 48, peer reviewed
May/June 2012
M. Pavan, E. Fioravanzo, A. Bassan, A. Mostrag-Szlichtyng, A.P. Worth, A. Conto

I modelli in silico QSAR per la valutazione genotossica e cancerogena delle impurezze

16° Congresso Nazionale della Società Italiana di Tossicologia (SITOX) Giardini Naxos (ME)
March 21-23, 2012
A. Conto, I. Caldera et al.

Il contenimento nella lavorazione di farmaci ad alta attività.

Linea guida AFI, Buone Pratiche di fabbricazione, Volume VIII
2012

Publications 2011-2007

A. Conto

The mutual recognition procedure on biocidal products in EU

Chemistry today, vol 29, n. 6
November/December 2011
A.Conto, J. Cantavella

From Directives to Regulations. The new trends of the European policy for chemical safety

Chemistry Pharmachem 2011
2011
A. Conto

The transition from the old national system to the BPD biocidal product authorisation, The Italian case

Chemistry Today, Vol., N. 6
November/December 2010
A. Conto, L. De Luca

Writing a Chemical Safety Report, Expertise in different fields is needed

Chemistry Today, Focus on REACH, Vol. 27, no. 4. page 30
July/August 2009
A. Conto

A new approach for the safety assessment of botanicals intended for use as ingredients in food supplements.

Agro Food magazine, Vol 20, n.3, page 12
May/June 2009
A. Conto, E. Meriano, L. Viani. L. Savin, L. De Luca

The Chemical Safety Assessment for Occupational Health Characterisation of the dose-response for human health and the Risk Assessment.

PharmChem, Year 8, Number 1-2, page 2-3
February 2009
A. Conto, L. De Luca

REACH Criteria for PBT assessment. How to approach the evaluation of Persistence, Bioaccumulation and Toxic properties of chemical substances.

Book of abstracts of the XXIII National Congress of the Italian Chemical Society, Divisione di Chimica dell’ambiente e dei Beni Culturali, page 53
2009
A. Conto

REACH! The last news!

ICP magazine, page 22-23
November 2008
Interview to A. Conto and others

REACH, a real opportunity?

Laboratorio 2000, n. 6, pages 34-41
September 2008
A. Conto

Technical aspect for the application of REACH in the chemical-pharmaceutical companies

Abstract book, 48° AFI symposium, page 70
June 2008
A. Conto

Interview by Laboratorio 2000

Laboratorio 2000, page 70
April 2008
A. Conto, I. Caldera et al.

Guide to the REACH

Regulation AFI association
February 2008
A. Conto, E. Meriano, L. Viani

The Safety Data under REACH, Quality and Sharing procedure

Focus on REACH, Chemistry Today, page 27-28
January/February 2008
A. Conto, E. Meriano, L. Viani

Chemsafe Company Presentation

Chemistry Today, page 61/62
November/December 2007
A. Conto, E. Meriano, L. Viani

The evolution of the Safety Data Sheet within the European Regulatory Legislation “From the past to the REACH format”.

Pharmachem, page 13
October 2007
A. Conto, E. Meriano, L. Viani

The Business implication related to REACH

Pharmachem, page 6
January/February 2007
A. Conto, E. Meriano, L. Viani

Approching the new EU REACH Regulation, The Action Plan.

Chemistry Today; Focus on REACH Regulation Page IV, Vol. 25, n.1
January 2007

Publications 2006-2002

A. Conto, E. Meriano

Un corretto approccio al REACH, la valutazione preliminare del portafoglio prodotti e la valutazione del budget

La Chimica e l’Industria, page 24
June 2006
A. Conto, E. Meriano

Alternatives to animal testing, a current challenge

Pharmachem, page 38
October 2005
A. Conto, E. Meriano

Environmental Risk Assessment of Pharmaceuticals

Chemistry Today, page 62-64
September/October 2005
A. Conto, E. Meriano

REACH: La nuova legislazione europea sulla sicurezza delle sostanze chimiche

Opuscolo informativo per le aziende del settore issued by Chemsafe
September 2005
N. Corsico, F. Pizzocheri, A. Conto

Nutraceuticals, a simple approach for establishing safety and efficacy

Agro Food, Industry and biotech., page 54
September/October 2004
E. Meriano, A. Conto, F. Pizzocheri

The global harmonisation system (GSH) for the classification and labelling of chemicals

POSTER, IUTOX 2004, Tampere, Finland.
July 10-15, 2004
A. Conto

The history of European legislation on chemical safety

Chemistry Today/Chimica oggi, page 62
June 2004
A. Conto

The Precautionary Approach within the future EU Chemical Policy; Science and Business implications

Pharmachem, Volume no. October 2003
October 2003
A. Conto, F. Pizzocheri

Pharma Intermediates Safety Evaluation, a Reduced Toxicology Programme

POSTER, Eurotox 2003, Florence, Italy
September 28-October 1, 2003
A. Conto, F. Pizzocheri

The future European policy on Safety of Chemical Substances

POSTER, Eurotox 2003, Florence, Italy
September 28-October 1, 2003
F. Pizzocheri, A. Conto, N. Corsico

A Standardized and reliable approach to the assessment of safety and efficacy of nutraceuticals

POSTER, Eurotox 2003, Florence, Italy
September 28-October 1, 2003
A. Conto, E. Fino

Reduced test Package for Pharma Intermediates notification, a new opportunity for the industry

Outsourcing compendium 2003, page 14-15
2003
A. Conto

Handling Hazaurdous Chemicals and Pharmaceuticals

Encyclopedia of Pharmaceutical Technology, II Edition, Volume 1 Edited by Marcel Dekker Inc.
2003
A. Conto

Aspetti Farmaco-tossicologici e classificazione dei farmaci

Notiziario Chimico-Farmaceutico, pag. 78-81
December 2002
A. Conto, E. Fino

Reduced test Package for Pharma Intermediates notification, a new opportunity for the industry

Chemistry Today, no. 9, page 47-48
September 2002

Publications 2001-1997

A. Conto, P. Gnemi

Un caso di riutilizzo e classificazione di un rifiuto solido

Workshop ”Il Decreto Ronchi. Metodologie e casi di riutilizzo di rifiuti solidi”, BioIndustry Park del Canavese (BiPCa Spa)
March, 2001
P. Gnemi, A. Conto

Un nuovo approccio nella gestione dei reflui. L’esempio americano

Workshop ”Il testo unico sulla acque, problematiche industriali”, BioIndustry Park del Canavese (BiPCa Spa)
February, 2001
P. Gnemi, A. Conto

Harmonizing the notification procedures (EU, USA, Japan)

Presented lecture, Charles Simeons Conference, London
November 15, 2000
A. Conto, P. Gnemi

New Strategies in designing new chemicals

Chemical Market Reporter, vol. 258, no.18
October 30, 2000
A. Conto, P. Gnemi

Le richieste regolatorie internazionali in campo ecotossicologico

Presented lecture, 1th Convegno Nazionale di Ecotossicologia, Torino
July 7, 2000
P. Gnemi, A. Conto

New initiatives for chemical safety

Chemical Market Reporter, vol. 257, no.7
Febbraio 14, 2000
P. Gnemi, A. Conto

Notification programmes case studies

Oral presentation at the CPhI Conference 99 Frankfurt, Germany
December 2-4, 1999
A. Conto, P. Gnemi

The chemical industry client in a CRO prospective

Chemistry Today, Outsourcing
November - December, 1999

Publications 1996-1992

R. Peascador, R. Tettamanti, L. Salvetti, A. Conto, D. Barone, R. Porta, M. Mantovani, L. Ferro

Effects of Defibrotide on leukocytosis in rabbits with diet induced atherosclerosis

Presented during the 66th Congress of the European Atherosclerosis Society Florence, Italy
July 13-17, 1996
S. Peano, A. Nyska, G.E. Bestetti, A. Conz, P. Marinelli, M. Carbonatto, A. Conto

Spontaneous female genital tract granular cell tumors (GCT) in the Sprague-Dawley rat. Immunohistochemical comparison with the meningeal GCT

Toxicology Letters – Suppl. 1/74 1-106
August, 1994
R. Porta, A. Conz, A. Conto, R. Pescador, M. Mantovani, L. Ferro

Comparable beneficial effects of Defibrotide and Nifedipine in calcium induced atherosclerosislife science

Vol. 54, No. 12, pp. 799 – 812
1994